Commentary The statin-low cholesterol-cancer conundrum
نویسندگان
چکیده
U. RAVNSKOV, K.S. McCULLY and P.J. ROSCH From the Independent investigator, Magle Stora Kyrkogata 9, 22350 Lund Sweden, Pathology and Laboratory Medicine Service VA Boston Healthcare System, West Roxbury MA, USA, Department of Pathology, Harvard Medical School, Boston MA, Clinical Professor of Medicine and Psychiatry, New York Medical College and President, The American Institute of Stress 124 Park Ave. Yonkers, New York, USA
منابع مشابه
Statin a day keeps cancer at bay. [World J Clin Oncol. 2013] - PubMed - NCBI
Abstract In addition to cholesterol reduction, statins, currently the most commonly prescribed drug in the world, have been shown to have anti-neoplastic and immunomodulatory effects. Several observational studies and meta-analyses have shown reduction in risk of multiple cancers. More recently there has been an increasing interest in the potential role of statins as adjuvant therapy after canc...
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BACKGROUND The risk association between low-density lipoprotein (LDL) cholesterol and cancer remains controversial and largely unexplored for people not receiving statin therapy. METHODS We examined the risk association between LDL cholesterol and cancer among patients with type 2 diabetes mellitus who were free of cancer at enrolment and whose statin use was known. We considered a variety of...
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The efficacy and safety of Salvia officinalis combined with statin have not been evaluated in dyslipidemic diabetes mellitus type 2 (DDMT2) so far. The plant extract antioxidant activity was determined by the DPPH radical scavenging assay. The total flavonoid, total phenolic and quercetin contents of the capsules containing the plant extract were also measured. Moreover, the effects of 2-month ...
متن کاملStatins, low-density lipoprotein cholesterol, and risk of cancer.
OBJECTIVES We sought to assess whether statin-mediated reductions in low-density lipoprotein cholesterol (LDL-C) are associated with an increased risk of cancer. BACKGROUND We recently reported an inverse association between on-treatment LDL-C levels and incident cancer in statin-treated patients enrolled in large randomized controlled trials, raising concern that LDL-C lowering by statins ma...
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تاریخ انتشار 2011